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1

Sodium–glucose co‐transporter 2 inhibition with empagliflozin improves cardiac function in non‐diabetic rats with left ventricular dysfunction after myocardial infarction

Yurista, Salva R., Silljé, Herman H.W., Oberdorf‐Maass, Silke U., Schouten, Elisabeth‐Maria, Pavez Giani, Mario G., Hillebrands, Jan‐Luuk, van Goor, Harry, van Veldhuisen, Dirk J., de Boer, Rudolf A.,

Journal:

European Journal of Heart Failure

Year:

2019

Language:

english

File:

PDF, 2.73 MB

english, 2019

2

Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases

Herman H.W. Silljé, Erich A. Nigg

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 337 KB

english, 2001

3

Vitamin D status and outcomes in heart failure patients

Liu, Licette C.Y., Voors, Adriaan A., van Veldhuisen, Dirk J., van der Veer, Eveline, Belonje, Anne M., Szymanski, Mariusz K., Silljé, Herman H.W., van Gilst, Wiek H., Jaarsma, Tiny, de Boer, Rudolf A

Journal:

European Journal of Heart Failure

Year:

2011

Language:

english

File:

PDF, 215 KB

english, 2011

4

Novel heart failure biomarkers: why do we fail to exploit their potential?

Piek, Arnold, Du, Weijie, de Boer, Rudolf A., Silljé, Herman H. W.

Journal:

Critical Reviews in Clinical Laboratory Sciences

Year:

2018

Language:

english

File:

PDF, 1.71 MB

english, 2018

5

OPLAH ablation leads to accumulation of 5-oxoproline, oxidative stress, fibrosis and elevated fillings pressures: a murine model for heart failure with a preserved ejection fraction

Pol, Atze van der, Gil, Andres, Tromp, Jasper, Silljé, Herman H W, van Veldhuisen, Dirk J, Voors, Adriaan A, Hoendermis, Elke S, Grote Beverborg, Niels, Schouten, Elisabeth-Maria, de Boer, Rudolf A, B

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 932 KB

english, 2018

6

Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update

Suthahar, Navin, Meijers, Wouter C., Silljé, Herman H.W., Ho, Jennifer E., Liu, Fu-Tong, de Boer, Rudolf A.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

7

Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure

Meimei Yin, Herman HW Silljé, Maxi Meissner, Wiek H van Gilst, Rudolf A de Boer

Journal:

Cardiovascular Diabetology

Year:

2011

Language:

english

File:

PDF, 494 KB

english, 2011

8

Heart failure-associated anemia: bone marrow dysfunction and response to erythropoietin

Willem-Peter T. Ruifrok, Cheng Qian, Herman H. W. Silljé, Harry van Goor, Dirk J. van Veldhuisen, Wiek H. van Gilst, Rudolf A. de Boer

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 563 KB

english, 2011

9

Regulation of Aurora-A kinase on the mitotic spindle

Thomas A. Kufer, Erich A. Nigg, Herman H. W. Silljé

Journal:

Year:

2003

Language:

english

File:

PDF, 217 KB

english, 2003

10

The histone chaperone Asf1 is dispensable for direct de novo histone deposition inXenopusegg extracts

Dominique Ray-Gallet, Jean-Pierre Quivy, Herman W. W. Silljé, Erich A. Nigg, Geneviève Almouzni

Journal:

Year:

2007

Language:

english

File:

PDF, 603 KB

english, 2007

11

Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora

Eunice H. Y. Chan, Anna Santamaria, Herman H. W. Silljé, Erich A. Nigg

Journal:

Year:

2008

Language:

english

File:

PDF, 696 KB

english, 2008

12

Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1

Neef, Rüdiger, Gruneberg, Ulrike, Kopajtich, Robert, Li, Xiuling, Nigg, Erich A., Sillje, Herman, Barr, Francis A.

Journal:

Nature Cell Biology

Year:

2007

Language:

english

File:

PDF, 1.60 MB

english, 2007

13

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

Gruss, Oliver J., Wittmann, Malte, Yokoyama, Hideki, Pepperkok, Rainer, Kufer, Thomas, Silljé, Herman, Karsenti, Eric, Mattaj, Iain W., Vernos, Isabelle

Journal:

Nature Cell Biology

Year:

2002

Language:

english

File:

PDF, 1.83 MB

english, 2002

14

Polo-like kinases and the orchestration of cell division

Barr, Francis A., Silljé, Herman H. W., Nigg, Erich A.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2004

Language:

english

File:

PDF, 268 KB

english, 2004

15

Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2

Hanisch, Anja, Silljé, Herman H W, Nigg, Erich A

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 643 KB

english, 2006

16

Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1

Krause, Darren R, Jonnalagadda, Jyoti C, Gatei, Magtouf H, Sillje, Herman HW, Zhou, Bin-Bing, Nigg, Erich A, Khanna, Kumkum

Journal:

Year:

2003

Language:

english

File:

PDF, 427 KB

english, 2003

17

The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1

Chan, Eunice H Y, Nousiainen, Marjaana, Chalamalasetty, Ravindra B, Schäfer, Anja, Nigg, Erich A, Silljé, Herman H W

Journal:

Year:

2005

Language:

english

File:

PDF, 283 KB

english, 2005

18

Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication

Journal:

The EMBO Journal

Year:

1999

Language:

english

File:

PDF, 595 KB

english, 1999

19

HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes

Herman H.W. Silljé, Susanna Nagel, Roman Körner, Erich A. Nigg

Journal:

Current Biology

Year:

2006

Language:

english

File:

PDF, 879 KB

english, 2006

20

The Spindle Protein CHICA Mediates Localization of the Chromokinesin Kid to the Mitotic Spindle

Anna Santamaria, Susanna Nagel, Herman H.W. Sillje, Erich A. Nigg

Journal:

Current Biology

Year:

2008

Language:

english

File:

PDF, 1.38 MB

english, 2008

21

Regulation of the (pro)renin–renin receptor in cardiac remodelling

Hasan Mahmud, Herman H. W. Silljé, Megan V. Cannon, Wiek H. van Gilst, Rudolf A. de Boer

Journal:

Journal of Cellular and Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 212 KB

english, 2012

22

The glucose-6-phosphate-isomerase reaction is essential for normal glucose repression in Saccharomyces cerevisiae

Laurens N. SIERKSTRA, Herman H. W. SILLJÉ, John M. A. VERBAKEL, C. Theo VERRIPS

Journal:

Year:

1993

Language:

english

File:

PDF, 714 KB

english, 1993

23

Direct Regulation of tRNA and 5S rRNA Gene Transcription by Polo-like Kinase 1

Jennifer A. Fairley, Louise E. Mitchell, Tracy Berg, Niall S. Kenneth, Conrad von Schubert, Herman H.W. Silljé, René H. Medema, Erich A. Nigg, Robert J. White

Journal:

Year:

2012

Language:

english

File:

PDF, 1014 KB

english, 2012

24

Direct Regulation of tRNA and 5S rRNA Gene Transcription by Polo-like Kinase 1

Jennifer A. Fairley, Louise E. Mitchell, Tracy Berg, Niall S. Kenneth, Conrad von Schubert, Herman H.W. Silljé, René H. Medema, Erich A. Nigg, Robert J. White

Journal:

Year:

2012

Language:

english

File:

PDF, 480 KB

english, 2012

25

Purification of mitotic spindles from cultured human cells

Herman H.W. Silljé, Erich A. Nigg

Journal:

Year:

2006

Language:

english

File:

PDF, 150 KB

english, 2006

26

Phosphoproteome analysis of the human mitotic spindle

Nousiainen, M., Sillje, H. H. W., Sauer, G., Nigg, E. A., Korner, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 29 KB

english, 2006

27

The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload

Laura M.G. Meems, Megan V. Cannon, Hasan Mahmud, Adriaan A. Voors, Wiek H. van Gilst, Herman H.W. Silljé, Willem P.T. Ruifrok, Rudolf A. de Boer

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 685 KB

english, 2012

28

ERYTHROPOIETIN RECEPTOR DEFICIENT MICE HAVE IMPAIRED CARDIAC ADAPTATION DURING VOLUNTARY EXERCISE

Willem-Peter T. Ruifrok, Laura M. Meems, B. Daan Westenbrink, Alexander H. Maass, Herman H. Sillje, Dirk J. van Veldhuisen, Wiek H. van Gilst, Rudolf A. de Boer

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 60 KB

english, 2010

29

Suicidal erythrocyte death, eryptosis, as a novel mechanism in heart failure-associated anaemia

Mahmud, H., Ruifrok, W. P. T., Westenbrink, B. D., Cannon, M. V., Vreeswijk-Baudoin, I., van Gilst, W. H., Sillje, H. H. W., de Boer, R. A.

Journal:

Cardiovascular Research

Year:

2013

Language:

english

File:

PDF, 704 KB

english, 2013

30

Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination

Krajewska, M, Heijink, A M, Bisselink, Y J W M, Seinstra, R I, Silljé, H H W, de Vries, E G E, van Vugt, M A T M

Journal:

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

31

The WAP Four-Disulfide Core Domain Protein HE4: A Novel Biomarker for Heart Failure

de Boer, Rudolf A., Cao, Qi, Postmus, Douwe, Damman, Kevin, Voors, Adriaan A., Jaarsma, Tiny, van Veldhuisen, Dirk J., Arnold, William D., Hillege, Hans L., Silljé, Herman H.W.

Journal:

Journal of the American College of Cardiology: Heart Failure

Year:

2013

Language:

english

File:

PDF, 247 KB

english, 2013

32

Short-term vitamin D3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: An open-label, blinded end point, randomized prospective trial (VitD-CHF trial)

Schroten, Nicolas F., Ruifrok, Willem P.T., Kleijn, Lennaert, Dokter, Martin M., Silljé, Herman H., Lambers Heerspink, Hiddo J., Bakker, Stephan J.L., Kema, Ido P., van Gilst, Wiek H., van Veldhuisen,

Journal:

American Heart Journal

Year:

2013

Language:

english

File:

PDF, 345 KB

english, 2013

33

Loss of mitochondrial exo/endonuclease EXOG affects mitochondrial respiration and induces ROS-mediated cardiomyocyte hypertrophy

Tigchelaar, Wardit, Yu, Hongjuan, de Jong, Anne Margreet, van Gilst, Wiek H., van der Harst, Pim, Westenbrink, B. Daan, de Boer, Rudolf A., Silljé, Herman H. W.

Journal:

AJP Cell Physiology

Year:

2015

Language:

english

File:

PDF, 15.30 MB

english, 2015

34

DHRS7c , a novel cardiomyocyte-expressed gene that is down-regulated by adrenergic stimulation and in heart failure

Lu, Bo, Tigchelaar, Wardit, Ruifrok, Willem P.T., van Gilst, Wiek H., de Boer, Rudolf A., Silljé, Herman H.W.

Journal:

European Journal of Heart Failure

Year:

2012

Language:

english

File:

PDF, 1.21 MB

english, 2012

35

Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle

Borgdorff, Marinus A.J., Bartelds, Beatrijs, Dickinson, Michael G., Boersma, Bibiche, Weij, Michel, Zandvoort, Andre, Silljé, Herman H.W., Steendijk, Paul, de Vroomen, Maartje, Berger, Rolf M.F.

Journal:

European Journal of Heart Failure

Year:

2012

Language:

english

File:

PDF, 362 KB

english, 2012

36

Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo

Kuipers, Irma, Li, Jiang, Vreeswijk-Baudoin, Inge, Koster, Johan, van der Harst, Pim, Silljé, Herman H.W., Kuipers, Folkert, van Veldhuisen, Dirk J., van Gilst, Wiek H., de Boer, Rudolf A.

Journal:

European Journal of Heart Failure

Year:

2010

Language:

english

File:

PDF, 449 KB

english, 2010

37

Clinical symptoms of right ventricular failure in experimental chronic pressure load are associated with progressive diastolic dysfunction

Borgdorff, Marinus A.J., Koop, Anne Marie C., Bloks, Vincent W., Dickinson, Michael G., Steendijk, Paul, Sillje, Herman H.W., van Wiechen, Maarten P.H., Berger, Rolf M.F., Bartelds, Beatrijs

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 2.32 MB

english, 2015

38

Pharmacological inhibition of galectin-3 protects against hypertensive nephropathy

Frenay, Anne-Roos S., Yu, Lili, van der Velde, A. Rogier, Vreeswijk-Baudoin, Inge, López-Andrés, Natalia, van Goor, Harry, Silljé, Herman H., Ruifrok, Willem P., de Boer, Rudolf A.

Journal:

AJP: Renal Physiology

Year:

2015

Language:

english

File:

PDF, 927 KB

english, 2015

39

Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission

Chalamalasetty, R. B., Hummer, S., Nigg, E. A., Sillje, H. H. W.

Journal:

Journal of Cell Science

Year:

2006

Language:

english

File:

PDF, 5.34 MB

english, 2006

40

Glucagon-Like Peptide 1 Prevents Reactive Oxygen Species-Induced Endothelial Cell Senescence Through the Activation of Protein Kinase A

Oeseburg, H., de Boer, R. A., Buikema, H., van der Harst, P., van Gilst, W. H., Sillje, H. H. W.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

41

SIGNAL TRANSDUCTION: Capturing Polo Kinase

W. Sillje, H. H.

Journal:

Year:

2003

Language:

english

File:

PDF, 218 KB

english, 2003

42

The Plk1-dependent Phosphoproteome of the Early Mitotic Spindle

Santamaria, A., Wang, B., Elowe, S., Malik, R., Zhang, F., Bauer, M., Schmidt, A., Sillje, H. H. W., Korner, R., Nigg, E. A.

Journal:

Molecular & Cellular Proteomics

Year:

2011

Language:

english

File:

PDF, 3.96 MB

english, 2011

43

Nitrogen-regulated transcription and enzyme activities in continuous cultures of Saccharomyces cerevisiae

ter Schure, E. G., Sillje, H. H. W., Raeven, L. J. R. M., Boonstra, J., Verkleij, A. J., Verrips, C. T.

Journal:

Microbiology (Society for General Microbiology)

Year:

1995

Language:

english

File:

PDF, 1.16 MB

english, 1995

44

AKIP1, a Cardiac Hypertrophy Induced Protein that Stimulates Cardiomyocyte Growth via the Akt Pathway

Yu, Hongjuan, Tigchelaar, Wardit, Lu, Bo, van Gilst, Wiek, de Boer, Rudolf, Westenbrink, B., Silljé, Herman

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

45

The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects

Cannon, Megan V., Yu, Hongjuan, Candido, Wellington M., Dokter, Martin M., Lindstedt, Eva-Lotte, Silljé, Herman H.W., van Gilst, Wiek H., de Boer, Rudolf A.

Journal:

European Journal of Heart Failure

Year:

2015

Language:

english

File:

PDF, 641 KB

english, 2015

46

Metformin improves cardiac function in a nondiabetic rat model of post-MI heart failure

Yin, M., van der Horst, I. C. C., van Melle, J. P., Qian, C., van Gilst, W. H., Sillje, H. H. W., de Boer, R. A.

Journal:

AJP Heart and Circulatory Physiology

Year:

2011

Language:

english

File:

PDF, 2.27 MB

english, 2011

47

Renal Handling of Galectin-3 in the General Population, Chronic Heart Failure, and Hemodialysis

Meijers, W. C., van der Velde, A. R., Ruifrok, W. P., Schroten, N. F., Dokter, M. M., Damman, K., Assa, S., Franssen, C. F., Gansevoort, R. T., van Gilst, W. H., Sillje, H. H., de Boer, R. A.

Journal:

Journal of the American Heart Association

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

48

Identification of hypertrophy- and heart failure-associated genes by combining in vitro and in vivo models

Lu, B., Yu, H., Zwartbol, M., Ruifrok, W. P., van Gilst, W. H., de Boer, R. A., Sillje, H. H. W.

Journal:

Physiological Genomics

Year:

2012

Language:

english

File:

PDF, 641 KB

english, 2012

49

LXRα improves myocardial glucose tolerance and reduces cardiac hypertrophy in a mouse model of obesity-induced type 2 diabetes

Cannon, Megan V., Silljé, Herman H. W., Sijbesma, Jürgen W. A., Khan, Mohsin A. F., Steffensen, Knut R., van Gilst, Wiek H., de Boer, Rudolf A.

Journal:

Year:

2016

Language:

english

File:

PDF, 869 KB

english, 2016

50

Phosphorylation by Cdk1 Induces Plk1-Mediated Vimentin Phosphorylation during Mitosis

Tomoya Yamaguchi, Hidemasa Goto, Tomoya Yokoyama, Herman Silljé, Anja Hanisch, Andreas Uldschmid, Yasushi Takai, Takashi Oguri, Erich A. Nigg and Masaki Inagaki

Journal:

The Journal of Cell Biology

Year:

2005

Language:

english

File:

PDF, 834 KB

english, 2005

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